Glucosamine HCl



Glucosamine HCl is critical for maintaining healthy human joints because it is a precursor in the formation of glycosaminoglycan, a major component of healthy human cartilage. Glucosamine HCl is typically extracted from crustacean shells which contain a high percentage of this vital material.

Glucosamine HCl, combined with Chondroitin Sulfate, was part of an extensive five year study by the National Institute of Health evaluating joint pain relief. Glucosamine, alone or in combination with Chondroitin Sulfate, has been a dietary supplement taken to relieve joint pain for more than twenty years and continues to be a significant treatment for joint pain relief.


Pharmore Ingredients conducts ongoing robust auditing process to ensure that we are working with manufacturing plants that are committed to making a quality program and follow Good Manufacturing Practices (GMPs). We ensure that they implement a continuous improvement program with critical double checks throughout their process.


Typical Process Flow:


Glucosamine products provided by Pharmore Ingredients are crustacean derived.


Crustacean shells that contain glucosamine HCl are mixed with acid to digest the shells.


The glucosamine HCl in the acid slurry is cooled and gluosamine HCl crystals are formed.


The glucosamine HCl crystal slurry is centrifuged to separate the glucosamine crystals.


The glucosamine HCl crystals are dissolved in water and activated charcoal is added to remove any extraneous shell materials.


The purified glucosamine HCl solution is filtered to remove the charcoal and any remaining extraneous materials.


The purified glucosamine HCl solution is vacuum dried to remove water, leaving only purified glucosamine HCl crystals.


The glucosamine HCl crystals are rinsed with alcohol to further purify.


The final purified glucosamine HCl is centrifuged, milled, screened and passed over a metal detector as final step to remove any potential contaminants before packaging.


Frequently Asked Questions:


1. Which form of Glucosamine is the best?

  • There are several forms of Glucosamine. Glucosamine HCl is the most common form purchased and has the highest level of Glucosamine content. Pharmore can provide you with the Glucosamine content on several Glucosamine forms such as Glucosamine HCl, Glucosamine Sulfate 2KCl, Glucosamine Sulfate 2NaCl, etc upon request.

2. How do I formulate with Glucosamine HCl?

  • First you need to decide on how you refer to the Glucosamine HCl on the label and formulate for the complex that you are claiming whether it is Glucosamine or Glucosamine HCl. Pharmore can provide the content calculation sheet to assist you.



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